Accepted List of Alternatives


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1. PETA/PISC
(2019.10.05 Update)

The alternative methods endorsed by the Organisation for Economic Co-operation and Development (OECD), the European Union Reference Laboratory for alternatives to animal testing (EURL ECVAM), the Japanese Center for the Validation of Alternative Methods (JaCVAM), the Korean Center for the Validation of Alternative Methods (KoCVAM), and/or the U.S. Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) are listed by PETA-SCI.

Website:https://www.thepsci.eu/alternatives/

List

2. U.S. EPA
(2021.2.18 Update)

US EPA has updated its list of alternative test methods or strategies (New Approach Methodologies or NAMs) that do not require new vertebrate animal testing. This action helps meet the requirements of the Toxic Substances Control Act to reduce and replace, to the extent practicable and scientifically justified, the use of vertebrate animals in the testing of chemical substances or mixtures.

Strategic Plan to Reduce the Use of Vertebrate Animals in Chemical Testing

2019 Update 2021 Update

3. NICEATM
(2021.03.25 Update)

Alternative Methods Accepted by US Agencies

(1) Methods for chemical safety testing that are accepted by U.S. and international regulatory authorities as replacement, reduction, or refinement alternatives to required animal tests

(2) Guidances to support replacement, reduction, or refinement alternatives to animal use for required testing: these documents are recommendations that do not necessarily establish legally enforceable responsibilities

NICEATM list